95-70-5

Toluene-2,5-diamine is a permanent hair dye involved in contact dermatitis in hairdressers and consumers. It does not cross-react with PPD, but cosensitization is frequent.

R20/21:Harmful by inhalation and in contact with skin .
R25:Toxic if swallowed.
R43:May cause sensitization by skin contact.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .

S24:Avoid contact with skin .
S37:Wear suitable gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .

Poison by ingestion and subcutaneous routes. A skin irritant. Mutation data reported. Questionable carcinogen. Has a toxic action upon the liver and can cause fatty degeneration of that organ. Its total effect upon the body seems to take place three chfferent ways. It is toxic to the central nervous system, producing jaundice by action on the liver and spleen, and anemia by destruction of the red blood cells. This action is quite similar to that of aniline, although by no means identical with it. Its high boiling point and the fact that the material is solid at room temperature make it somewhat less hazardous than aniline, particularly at ordinary working temperatures. The literature contains a reference to a permanent injury to an eye due to the use of this material as an eyelash dye. It is considered to be an irritating dye material. When heated to decomposition it emits toxic fumes of NOx. See also other toluene diamine entries and AROMATIC AMINES.