N-methyl-N-dithiocarboxyglucamine (684-2736 mg/kg; i.p., three daily injection) effectively promotes fecal Cd excretion over a 3-day period[1].
N-methyl-N-dithiocarboxyglucamine (2736 mg/kg; i.p., three times a week) reduces the kidney and liver Cd levels[1].
| Animal Model: | Mice with CdCl2 injection[1] |
| Dosage: | 684, 1368 and 2736 mg/kg |
| Administration: | Intraperitoneal injection; 684, 1368 and 2736 mg/kg, three daily injection |
| Result: | Dose-dependently increased fecal Cd excretion and caused a fecal Cd excretion of almost 30% of the administered Cd over a 3-day period at a dose of 2736 mg/kg.
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