9000-81-1

Name Anticholinesterase
CAS 9000-81-1
EINECS(EC#) 232-559-3
Molecular Formula NULL
MDL Number MFCD00081268

Chemical Properties

storage temp.  -20°C
solubility  H2O: 1 mg/mL
form  powder
color  slightly yellow
biological source human erythrocytes
Specific Activity 200-1,000units/mg protein
Major Application diagnostic assay manufacturing

Safety Data

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501
Hazard Codes  B
WGK Germany  3
F  10-21
Storage Class 11 - Combustible Solids
Toxicity
The inhibition of AChE by these anticholinesterases leads to an accumulation of endogenous ACh, and thus results in hyperactivation of cholinergic receptors. Signs of acute poisoning can include irritability, tremors, convulsions, and predominately parasympathetic effects, with death usually the result of respiratory failure. Since AChE is contained in erythrocytes, the assay of erythrocyte AChE activity can be used as a diagnostic tool to assess exposure to organophosphorus anticholinesterases.

Hazard Information

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