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light yellow crystalline powder

2-Bromo-6-fluoronitrobenzene is a hydrocarbon derivative, mainly used as an organic intermediate.

The structure of 2-bromo-6-fluoronitrobenzene contains a nitro unit with high electron-withdrawing properties, which can easily undergo aromatic nucleophilic substitution reactions under the attack of common nucleophiles such as alcohols or amines.

To a suspension of sodium perborate tetrahydrate (135.374 g., 886.4 mmol) in 500 mL of acetic acid at 55°C was added dropwise 2-bromo-6-fluoroaniline (33.685 g., 177.271 mmol) in 70 mL solution in acetic acid. The reaction mixture was stirred at 55° C.