The novel fermentation products fostriecin and analogs PD 113,270 and PD 113,271 are structurally related polyene lactone phosphates that have antitumor activity in vitro and in vivo.
Uses
PD 113270 (CL 1565-B) is an antitumor agent. PD 113270 exhibits inhibitory effects to yeasts[1].
References
[1] Tunac J B, et, al. Novel antitumor agents CI-920, PD 113,270 and PD 113,271. I. Taxonomy, fermentation and biological properties. J Antibiot (Tokyo). 1983 Dec;36(12):1595-600. DOI:10.7164/antibiotics.36.1595 [2] Mamber SW, et, al. Antimycotic effects of the novel antitumor agents fostriecin (CI-920), PD 113,270 and PD 113,271. J Antibiot (Tokyo). 1986 Oct;39(10):1467-72. DOI:10.7164/antibiotics.39.1467
