AA 863 is a 5-lipoxygenase inhibitor that has dose-dependent inhibitory effects on proliferation of human glioma cell lines.
Uses
AA863 is a 5-lipoxygenase inhibitor with activity in inhibiting the proliferation of human glioma cells. AA863 exhibits significant and dose-dependent inhibitory effects in monolayer cultured glioma cells with an IC50 of 9.0 micromolar[1].
References
[1] Effects of the 5-lipoxygenase inhibitors AA-863 and U-60,257 on human glioma cell lines DOI:10.1016/0952-3278(90)90153-c
