76296-71-4

Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87?μM) activities against the tyrosinase and moderate (IC50=1.59 μg/mL) antileishmanial activities[1][2].

[1] Devkota KP, et, al. Tyrosinase inhibitory and antileishmanial constituents from the rhizomes of Paris polyphylla. Nat Prod Res. 2007 Apr;21(4):321-7. DOI:10.1080/14786410701192777
[2] Singh SB, et, al. Spirostanol saponins from Paris polyphylla, structures of polyphyllin C, D, E and F. Phytochemistry.1980; 21(12): 2925-2929.