75533-14-1

U-58431 is an antibiotic isolated from the fermentation broth of Streptomyces helicus.

Sarubicin A (U-58431) is an antibiotic that inhibits Gram-positive and Gram-negative bacteria and has antitumor activity[1][2].

[1] Wang H, et al. Sarubicinols A–C, Cytotoxic Benzoxazoles from a Streptomyces[J]. Journal of Natural Products, 2022, 85(4): 1167-1173. DOI:10.1021/acs.jnatprod.1c00820
[2] Slechta L, et al. Fermentation, Isolation, Characterization And Structure Of Antibiotic U-58, 431[J]. The Journal of Antibiotics, 1980, 33(9): 919-923. DOI:10.7164/antibiotics.33.919