ChemicalBook CAS DataBase List 74639-14-8

74639-14-8

Name	Liquiritin apioside
CAS	74639-14-8
EINECS(EC#)	-0
Molecular Formula	C26H30O13
MDL Number	MFCD09260034
Molecular Weight	550.51
MOL File	74639-14-8.mol

Chemical Properties

Boiling point	904.5±65.0 °C(Predicted)
density	1.65±0.1 g/cm3 (20 ºC 760 Torr)
form	Solid
pka	7.70±0.40(Predicted)
color	White to light yellow
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChIKey	FTVKHUHJWDMWIR-DWMQJYMWSA-N
SMILES	O1[C@H]([C@@H]([C@@](C1)(O)CO)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)Oc3ccc(cc3)[C@H]4Oc5c(ccc(c5)O)C(=O)C4

Safety Data

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

Hazard Information

Spectrum Detail

Supplier

BioBioPha Co., Ltd.

Telephone0871-65217109 13211707573;

Websitehttp://www.biobiopha.com

ShangHai YuanYe Biotechnology Co., Ltd.

Telephone021-61312847 13636370518

Websitehttp://www.shyuanye.com

Chengdu Biopurify Phytochemicals Ltd.

Telephone+86-028-82633397 18982077548

Websitehttp://www.biopurify.cn

Shanghai Winherb Medical Technology Co., Ltd.

Telephone021-38218169 13341702378

Websitehttp://www.winherb.cn

Shanghai Tauto Biotech Co., Ltd.

Telephone021-51320588

Websitehttp://www.tautobiotech.com/

Bide Pharmatech Ltd.

Telephone400-400-164-7117 18317119277

Websitehttp://www.bidepharm.com

Sichuan Wei Keqi Biological Technology Co., Ltd.

Telephone028-81700200 18116577057

Websitehttps://www.weikeqi-biotech.com/

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Telephone0510-85629785 18013409632

Websitehttp://www.reading-chemicals.com

Shanghai Aspire Biological Technology Co., Ltd.

Telephone021-61317773

Websitehttp://www.aspirebio.com

Shanghai Kewel Chemical Co., Ltd.

Telephone021-64609169 18901607656

Websitehttp://www.kewelchem.com/

Nanjing Duolong Bio-tech Co.,Ltd.

Telephone 18905173768

Websitehttp://www.dolonchem.com

Wuhan ChemFaces Biochemical Co., Ltd.

Telephone18607101326 15172504745

Websitehttp://www.chemfaces.com

Shanghai Haozhixiang Biotechnology Co., Ltd

Telephone526763801 13301653310

Website

Beijing Solarbio Science & Tecnology Co., Ltd.

Telephone010-50973130 18101056239

Websitehttp://www.solarbio.com

Amadis Chemical Company Limited

Telephone571-89925085

Websitehttp://www.amadischem.com

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840 18892239720

Websitehttp://www.jm-bio.com/

Shanghai Yihe Biological Technology Co., Ltd.

Telephone021-68882955 17721395025

Websitehttp://www.yihefd.com/products/

Shanghai Uteam Biotechnology Co., Ltd.

Telephone021-36031160 13311776681

Websitehttps://www.shruji.com/

1of4

Related Products

Send Inquriy

Animal Model:	Laryngeal reflexe study in Sprague-Dawley rat (250-350 g) pups^[1]
Dosage:	10 μg/μL (diluted in saline)
Administration:	Intralaryngeal perfusion for 10 minutes or peri-treatment for 20 minutes, single dose
Result:	Significantly reduced the apneic responses to CAP, HCl, and DW, as well as attenuated the hypertension and bradycardia responses to these stimuli. Did not change the cardiorespiratory responses to AP. Peri-SLN treatment with Liquiritin apioside also suppressed the apnea, hypertension, and bradycardia responses to CAP, HCl, and DW, similar to the effect of intralaryngeal treatment.

Animal Model:	DSS-induced colitis model in C57BL/6 mice (male, 18–22 g, 8–10 weeks)^[2]
Dosage:	0.01 g/kg, 0.02 g/kg (diluted in saline)
Administration:	Oral gavaged for 10 days, once daily
Result:	Exhibited the same pathological changes as that of the ABX (DSS) group mice, specifically, comparable weight loss, DAI score, colon length, and histology score.