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Orange-yellow or orange-red oily liquid. It has a characteristic Seville orange aroma and aromatic bitterness. It is affected by light. Its litmus test in alcoholic solutions is neutral. It is unstable to strong acids and bases. It is readily soluble in water and miscible with anhydrous ethanol or an equal amount of glacial acetic acid. It is soluble in methyl benzoate, dimethyl phthalate, fixed oils, and mineral oil. It is slightly soluble in propylene glycol and insoluble in glycerin.

Bitter orange is grown in Asia and parts of the Mediterranean.

Bitter orange has been used traditionally as a sedative, an appetite stimulant, an insecticide for mosquitos, and for Tinea infections and dyspepsia. It is also used for anemia, kidney/bladder disorders, heart, and circulation. Topically bitter orange is used for inflammation of eyelids, conjunctivae, muscle pain, rheumatic pain, and phlibitis.

Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus aurantium, Rutaceae.