71845-66-4

Prostaglandin E₂ (PGE₂) isopropyl ester is a more lipophilic form of the free acid, PGE₂. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of PGs show greatly diminished receptor activity in vitro compared to the parent free acids.