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6(Z),9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosahexaenoic acid is a very long chain polyunsaturated fatty acid (VLCPUFA) that has been found in tunny, herring, cod-liver, pilot whale, sardine, and squalus-suclii-liver oils, bovine retina, and as a component of triglycerides and cholesterol esters in mouse and rat testis. It is produced from dietary linolenic acid via a series of elongation and Δ⁶-desaturation reactions in fish and rat brain and undergoes β-oxidation to form docosahexaenoic acid (DHA; Item No. 90310).

Nisinic acid (C24:6n-3) is a very long chain polyunsaturated fatty acid (VLCPUFA) that is a component of triglycerides and cholesterol esters in mouse and rat testis[1].

ChEBI: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoic acid is a very long-chain polyunsaturated fatty acid that is tetracosanoic acid having six double bonds located at positions 6, 9, 12, 15, 18 and 21 (the (6Z,9Z,12Z,15Z,18Z,21Z-isomer). It is an omega-3 fatty acid and a tetracosahexaenoic acid. It is a conjugate acid of a (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoate.

[1] Zhukova NV. Fatty Acids of Echinoderms: Diversity, Current Applications and Future Opportunities. Mar Drugs. 2022;21(1):21. Published 2022 Dec 27. DOI:10.3390/md21010021