90105-02-5

5(Z),8(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid that can be a substrate for 5-lipoxygenase (5-LO). 5-LO from RBL-1 cells converts this fatty acid to 5-hydroxy-6,8,14-eicosatrienoic acid and 5-hydroperoxy-6,8,14-eicosatrienoic acid. Due to the lack of a double bond at C-11, this particular fatty acid cannot be used in leukotriene A formation.¹

(5Z,8Z,14Z)-5,8,14-Eicosatrienoic acid is a biochemical assay reagent.

ChEBI: All-cis-icosa-5,8,14-trienoic acid is an icosatrienoic acid with three cis-double bonds at positions 5, 8 and 14.

Store at -20°C

1. Wei, Y., Evanst, R.W., Morrison, A.R., et al. Double bond requirement for the 5-lipoxygenase pathway Prostaglandins 29(4),537-545(1985).