67306-00-7

ChEBI: A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group.

Agricultural fungicide.

Moderately toxic by ingestion, inhalation, and skin contact.

fenpropidine, a piperidine derivative, and spiroxamine, a dioxolanemethyleneamine derivative introduced in 1996 , belong to the same group of fungicides.

Limited data are available in the open literature. Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1993). Fenpropidin is stable to aqueous hydrolysis and photodegradation. Hydroxylation of the piperidine ring is the primary metabolic pathway in soil and wheat plants. Hydroxylation and oxidation of one of the methyl groups of the tert-butyl moiety are the major reactions in rats and lactating goats. The primary metabolic pathways of fenpropidin are presented in Scheme 1.

Fenpropidin (1)i s stable to hydrolytic degradation (50 °C)in the pH range of 3-9 and when exposed to UV light in pH 5 buffer solution.