63775-95-1

Amorphous White Solid

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Cyclosporin B is a minor analogue of the cyclosporin complex produced by a number of different fungal genera including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin B possesses immunosuppressant and antifungal activities but has been much less extensively investigated than the major analogue, cyclosporin A.