6310-21-0

1634-04-4

62-53-3

6310-21-0

1. Aniline (1118 g, 0.012 mol), methyl tert-butyl ether (0.48 mol) and commercially available montmorillonite (3.83 g) were weighed into a 100 mL autoclave. 2. The autoclave was subjected to five successive displacements using nitrogen to ensure an oxygen-free reaction environment. 3. The reaction mixture was heated to 165 °C and mechanical stirring was initiated at a set stirring speed of 900 rpm. 4. Keep the reaction temperature within ±1°C of the set value for 4 hours. 5. Upon completion of the reaction, turn off the heating and stirring and allow the reaction mixture to cool naturally to room temperature. 6. remove the catalyst by centrifugation. 7. 7. Finally, the product was purified by distillation and chromatography to give O-tert-butylaniline with 98% purity.