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57-24-9

Name STRYCHNINE
CAS 57-24-9
EINECS(EC#) 200-319-7
Molecular Formula C21H22N2O2
MDL Number MFCD00005941
Molecular Weight 334.41
MOL File 57-24-9.mol

Chemical Properties

Appearance Strychnine is a colorless crystalline prisms or white powder. It is odorless; with a bitter taste
Melting point  284-286 °C(lit.)
alpha  D18 -104.3° (c = 0.254 in alc); D25 -139° (c = 0.4 in chloroform)
Boiling point  471.21°C (rough estimate)
density  d18 1.359
vapor pressure  1.5 xl0-7 Pa (20 °C, est.)
refractive index  1.6500 (estimate)
storage temp.  Poison room
solubility  chloroform: clear to hazy
form  Fine Crystalline Powder
pka 8.26(at 25℃)
Water Solubility  143 mg l-1
color  White
Stability: Stable. Incompatible with strong oxidizing agents.
Merck  8855
Exposure limits NIOSH REL: TWA 0.15 mg/m3, IDLH 3 mg/m3; OSHA PEL: TWA 0.15 mg/m3; ACGIH TLV: TWA 0.15 mg/m3.
LogP 1.930
CAS DataBase Reference 57-24-9(CAS DataBase Reference)
EPA Substance Registry System Strychnine (57-24-9)

Safety Data

Hazard Codes  T+,N
Risk Statements 
R27/28:Very Toxic in contact with skin and if swallowed .
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
Safety Statements 
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
RIDADR  UN 1692 6.1/PG 1
WGK Germany  3
RTECS  WL2275000
HazardClass  6.1(a)
PackingGroup  I
HS Code  29349990
Safety Profile
Human poison by ingestion. Experimental poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. Experimental reproductive effects. An allergen. Lethal dose to man: 30-60 mg/kg. If ingested, the time of action depends upon the condition of the stomach, whether empty or full, and the nature of the food present. If taken by subcutaneous injection, the place of administration of the injection will affect the time of action. The first symptoms are a feeling of uneasiness with a heightened reflex of irritability, followed by muscular twitching in some parts of the body. With larger doses, this is followed by a sense of impending suffocation. Convulsive movements begin that have the effect of mechanically causing the patient to cry out or to shriek; then follow the characteristic spasms, which set in with violence. These are at first clonic and then tonic. There are successive attacks of spasms. With each successive attack, the symptoms become more violent, eventually resulting in death. A rodenticide. When heated to decomposition it emits toxic fumes of NOx.
Hazardous Substances Data 57-24-9(Hazardous Substances Data)
Toxicity
LD50 i.v. (slow infusion) in rats: 0.96 mg/kg (Setnikar, Magistretti)
IDLA 3 mg/m3

Hazard Information

Material Safety Data Sheet(MSDS)

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