Neothramycin A is a pyrrol[1,4]benzodiazepine antibiotic.
Uses
Neothramycin A is an antibiotic, which can be isolated from Streptomyces. Neothramycin A exhibits board spectrum antimicrobial activity, inhibits Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisia with MIC of 25-50 μg/mL. Neothramycin A exhibits antitumor efficacy against leukemia in mouse models[1].
References
[1] Takeuchi T, et al., Neothramycins A and B, new antitumor antibiotics. J Antibiot (Tokyo). 1976 Jan;29(1):93-6. DOI:10.7164/antibiotics.29.93
