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Brain microsomes were able to metabolize tyramine to dopamine.

Tyramine is an endogenous compound which exists in the brain as a trace amine but is also an exogenous compound which is found in foods such as cheese and wine.

ChEBI: M-tyramine is a primary amino compound that is 2-phenylethanamine substituted by a hydroxy group at position 3. It has a role as a human urinary metabolite and a neurotransmitter. It is a member of tyramines and a primary amino compound. It is a conjugate base of a m-tyraminium.

Journal of Medicinal Chemistry, 27, p. 1321, 1984 DOI: 10.1021/jm00376a017

Human Endogenous Metabolite

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