ChemicalBook CAS DataBase List 58311-20-9

58311-20-9

Name	(3R,4R)-3-[(1,3-Benzodioxole-5-yl)methyl]-4-(3,4-dimethoxybenzyl)-4,5-dihydrofuran-2(3H)-one
CAS	58311-20-9
Molecular Formula	C21H22O6
Molecular Weight	370.4
MOL File	58311-20-9.mol

Chemical Properties

solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Cryst.

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Animal Model:	Female Sprague Dawley rats (7 weeks of age)^[1]
Dosage:	7 and 14 mg/kg
Administration:	Subcutaneous injection, 3 times a week for 2 weeks
Result:	Inhibited the mammary tumor growth and decreased tumor volume. Down-regulated c-Src, Erk1/2 and PI3K proteins and decreased Akt proteins. Inhibited downstream molecules in the cell cycle (c-Myc, E2f-1, CDK1 and cyclin B1) and metastasis (E-cadherin, MMP-2 and MMP-9).

58311-20-9

Chemical Properties

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