5743-36-2

Calcium Butyrate was used in the biological study in small intestine of pigs where Butyrate improved digestive and absorptive capacities.

Room temperature stirring, butyric acid 88.11g (1.0mol, 1.0eq) in 5 batches dissolved in 200mL of aqueous solution containing 45.0g sodium hydroxide, and then to the reaction solution slowly added 200mL of aqueous solution containing calcium chloride 108.

Recrystallise it from water (5mL/g) by partial evaporation in a desiccator and dry it in a vacuum to constant weight. [Pathak & Bhide J Indian Chem Soc 30 47, 48 1953.] Its dissociation constant at 25o is 0.29 [Colman-Porter & Monk J Chem Soc 4363 1952, Beilstein 2 IV 785].