55863-02-0

2695-47-8

74-89-5

55863-02-0

The following step: To a reaction flask was added a methanol solution containing 25% methylamine in an amount of 10 equivalents of methylamine. Subsequently 1 equivalent of 6-bromo-1-hexene was added to the reaction flask and mixed with stirring. The reaction mixture was heated to 40°C in an oil bath and kept at this temperature for 3 hours. Upon completion of the reaction, the mixture was cooled to 20 °C and 0.1 equivalent of p-methoxyphenol was added as a stabilizer, along with 1 equivalent of sodium hydroxide. The excess methylamine methanol solution was recovered under negative pressure. Next, the mixture was heated to 50 °C and a colorless liquid product, N-methyl-5-hexen-1-amine, was obtained by distillation under reduced pressure. The yield of this step was 67% and the purity of the product was 96.5%.