| Contact allergens |
Tixocortol 21-pivalate is a 21-ester of tixocortol, widely
used in topical treatments. It can induce severe allergic
contact dermatitis. This corticosteroid is a marker of the
allergenic A group that includes molecules without
major substitution on the D cycle (no C 16 methylation,
no C 17 side chain). A short-chain C 21 ester is possible.
Molecules are cloprednol, cortisone, fludrocortisone,
fluorometholone, hydrocortisone, methylprednisolone,
methylprednisone, prednisolone, prednisone, tixocor-
tol, and their C 21 esters (acetate, caproate or hexanoate,
phosphate, pivalate or trimethylacetate, succinate or
hemisuccinate, m-sulfobenzoate).
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