Hazard
Moderate fire risk.
Chemical Properties
clear colorless liquid
Chemical Properties
Methyl lactate is a colorless, transparent liquid.
Uses
Cellulose acetate solvent.
Definition
ChEBI: A lactate ester resulting from the formal condensation of the carboxy group of 2-hydroxypropanoic acid with methanol.
Production Methods
Methyl lactate is prepared by the esterification of methyl
alcohol with lactic acid . Methyl lactate is used as
a solvent for nitrocellulose, cellulose acetate, cellulose
acetobutyrate, cellulose acetopropionate, lacquers, and
stains . It is also used as a solvent for various forms
of cellulose, as a component in lacquers and stains, and as an
intermediate for an herbicide. Ethyl lactate can serve to
reduce the alkalinity in cosmetic preparations. It is also
used as a solvent for basic dyes, in the manufacture of lacquers and safety glass, as a solvent for various forms of
cellulose, as a component of varnishes, and as a food
flavoring agent. Cetyl lactate (hexadecyl 2-hydroxypropionate)
[CH3CHOOH)COOC16H33] occurs as a waxy solid.
Safety Profile
Methyl lactate has been classed as non-irritant to the eyes of guinea pigs.
The estimated average lethal dose for the female rat following i.p. injection of methyl lactate was >2000 mg/kg body weight. Observations included narcosis, respiratory distress and peritoneal adhesions. The estimated non toxic dose and estimated maximum dose without gross lesions at necropsy was 500 mg/kg body weight.
Synthesis
Methyl lactate is prepared by the esterification of methyl alcohol with lactic acid.
Purification Methods
Methyl lactate is easily hydrolyzed and often contains impurities such as free lactic acid, methanol and water. Free acid can be removed by washing after neutralization with alkali. Moisture can be removed by azeotropic distillation of an azeotropic mixture with benzene. Then, it was purified by distillation under reduced pressure. Since calcium chloride and the like form molecular compounds with methyl lactate, they cannot be used as desiccants. When the methyl lactate is mixed with water, it can be extracted and recovered with benzene, ether, etc.
