54010-75-2

Raw materials And Preparation Products

Hazard Information

Chemical Properties

white to light-grey powder

Uses

Zinc trifluoromethanesulfonate acts as a catalyst for the preparation of dithioketals. It is used as a Lewis acid catalyst in silylation reactions. It is also used as a catalyst for greener amine synthesis by reductive amination with hydrogen gas.

General Description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

reaction suitability

core: zinc
reagent type: catalyst

Synthesis

Triflic acid (0.056mol) was added dropwise to a suspension of zinc carbonate (0.02 mol)in dry methanol (20 ml) at room temperature. During the addition, CO2 was evolved. The mixture was stirred at 25°C for 20 minutes and refluxed for 2 h. The clear solution was cooled to 25°C and concentrated under reduced pressure. The resulting white powder was dried at 125°C for 2 h to afford Zinc trifluoromethanesulfonate (Zn(OTf)2 )(98% yield).

Purification Methods

It should be dried at 125o for 2hours at 3mm before use. It is soluble in CH2Cl2 but insoluble in pet ether. [Corey & Shimoji Tetrahedron Lett 24 169 1983.]

References

[1] Tetrahedron Letters, 2016, vol. 57, # 51, p. 5753 - 5756

Questions And Answer

• Reaction

  1. Catalyst for the addition of acetylenes to carbonyls and nitrones.
  2. Claisen rearrangement.
  3. Catalyst for the enantioselective Henry and Aza-Henry reactions.
  4. Pd-catalyzed hydroalkylation of styrenes with zinc reagents.
  ;

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

Related Products