537695-15-1

15-deoxy-Δ^12,14-Prostaglandin J₂ Glutathione (15-deoxy-Δ^12,14-PGJ₂ Glutathione) is a non-enzymatic adduct formed from 15-deoxy-Δ^12,14-PGJ₂ and glutathione.^1,2,3 The biological properties of this compound have not been characterized.

ChEBI: 15-deoxy-goyazensolide is a terpene lactone.

1. Cox, B., Murphey, L.J., Zackert, W.E., et al. Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J₂, to glutathione Biochim. Biophys. Acta 1584,37-45(2002).
2. Brunoldi, E.M., Zanoni, G., Vidari, G., et al. Cyclopentenone prostaglandin, 15-deoxy-Δ^12,14-PGJ₂, is metabolized by HepG2 cells via conjugation with glutathione Chem. Res. Toxicol. 20,1528-1535(2007).
3. Paumi, C.M., Smitherman, P.K., Townsend, A.J., et al. Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor γ (PPARγ) ligand, 15-deoxy-Δ^12,14 prostaglandin J₂ (15-d-PGJ₂). Biochemistry 43(8),2345-2352(2004).