53209-27-1

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from deer tongue grass and Apocynum venetum.

2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage[1][2].

ChEBI: 2''-galloylhyperin is a member of flavonoids and a glycoside.

[1] Wang P, et al. 2'-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo. Front Pharmacol. 2018 Jun 27;9:679. DOI:10.3389/fphar.2018.00679
[2] Wang P, et al. Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway. Food Chem Toxicol. 2017 Apr;102:129-142. DOI:10.1016/j.fct.2017.02.016