Enzyme inhibitor
This antibiotic (FWfree-acid = 359.40 g/mol; CAS 525-94-0; Water-soluble), also known as (2S,5R,6R)-6-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino] -3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (D-4-amino-4-carboxybutyl)-penicillinic acid, Adicillin?, Synnematin B?, as well as cephalosporin N, is produced by species of Cephalosporium as well as by Paecilomyces percicimus and Penicillium chrysogenum. (For details on mode of action, See Penicillins) Spectrum of Antibiotic Action: Penicillin N bacteriocida against Diplococcus pneumoniae, Proteus vulgaris, Salmonella typhimurium, Sarcina lutea, but shows little no activity against Bacillus subtilis and Staphylococcus aureus. Target(s): deacetoxycephalosporin-C hydroxylase; and deacetylcephalosporin-C acetyltransferase.
