508186-14-9

Ac-CoA Synthase Inhibitor can be prepared for the treatment of Compositions for neurological and cognitive diseases and disorders, particularly useful in the treatment of anxiety disorders and disorders such as phobias, panic disorders, psychosocial stress (such as seen in disasters, disasters or victims of violence), obsessive-compulsive disorders, generalized Anxiety disorders and post-traumatic stress disorder (PTSD).Also it may be used to modulate long-term memory storage or consolidation, to treat addiction and/or addiction-related diseases or conditions, to prevent or treat acute alcohol-induced memory Deficits and chronic alcohol-induced memory deficits.

Ac-CoA Synthase Inhibitor inhibits the incorporation of [14C]acetate into lipids in HepG2 cells with IC50 of 6.8 μM. It inhibits histone acetylation by [14C]acetate in HepG2 cells with IC50 of 5.5 μM.