ChemicalBook CAS DataBase List 480-22-8

480-22-8

Name	1,8,9-TRIHYDROXYANTHRACENE
CAS	480-22-8
Molecular Formula	C14H10O3
MDL Number	MFCD00001250
Molecular Weight	226.23
MOL File	480-22-8.mol

Chemical Properties

Appearance	yellow crystalline powder
Melting point	181 °C
Boiling point	327.84°C (rough estimate)
density	1.2022 (rough estimate)
refractive index	1.5767 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	6.23±0.30(Predicted)
color	Yellow powder
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	480-22-8(CAS DataBase Reference)
EPA Substance Registry System	1,8,9-Anthracenetriol (480-22-8)

Safety Data

RTECS	CB1225000
HS Code	2907.29.9000
Toxicity	mmo-sat 100 mg/plate BCSTB5 5,1489,77 less more

Hazard Information

General Description

Odorless yellow leaflets or needles; yellow powder. Tasteless. Filtrate from water suspension is neutral to litmus. When exposed to air, alkaline solutions turn red and lose their fluorescence.

Reactivity Profile

1,8,9-TRIHYDROXYANTHRACENE(480-22-8) is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. This chemical is incompatible with strong oxidizing agents. .

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for this chemical are not available. 1,8,9-TRIHYDROXYANTHRACENE is probably combustible.

Chemical Properties

yellow crystalline powder

Uses

Antipsoriatic.

Definition

ChEBI: An anthracenetriol that is anthracene substituted by hydroxy groups at positions 1, 8 and 9.

Brand name

Anthra-Derm (Dermik); DrithoCreme (Dermik); Drithoscalp (Dermik); Lasan (Stiefel).

Safety Profile

Questionable carcinogen withexperimental neoplastigenic and tumorigenic data.Mutation data reported. Skin contact can cause folliculitis.Absorption can cause kidney damage and intestinaldisturbances. Combustible when heated. When heated todecompositi

Purification Methods

Crystallise it from pet ether and pKEst ~dry it in vcuo.[Beilstein 6 IV 7602.]

Spectrum Detail

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