431996-53-1

Filastatin is a novel inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis.

Filastatin blocks the ability of Candida albicansand other Candida sp. to bind to polystyreneand human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.

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