Chemical Properties
white to light yellow crystal powder. Insoluble in cold water, slightly soluble in hot water, easily soluble in ethanol, ether, benzene and other organic solvents.
Physical properties
4-Amino-3,5-dichloroacetophenone is a white to light yellow crystal powder. Insoluble in cold water, slightly soluble in hot water, easily soluble in ethanol, ether, benzene and other organic solvents.
Uses
4-Amino-3,5-dichloroacetophenone is used to synthesize the drug Clenbuterol. Clenbuterol is a steroid-like chemical that was initially developed to treat asthma in horses, working by relaxing the airways in the animals'lungs.
Application
4-Amino-3,5-dichloroacetophenone is a compound useful in organic synthesis.
Preparation
3,5-Dichloro-4-aminoacetophenone was synthesized by chlorination of 4-aminoacetophenone. Add 4-aminoacetophenone and acetic acid (80%) into the reaction pot, stir and dissolve, quickly add chlorine-containing glacial acetic acid solution, the temperature of the addition is 5 °C, after the addition is completed, immediately put into ice water to precipitate the precipitate, filter, and wash with water to obtain the crude product Recrystallize with ethanol to obtain the finished product of 3,5-dichloro-4-aminoacetophenone.
