BMS641, also known as BMS209641, is a RARβ-selective agonist. BMS641 is a potential tumor suppressor.
Uses
BMS641 (BMS-209641) is a selective RARβ agonist. BMS641 has a higher affinity for RARβ (Kd, 2.5 nM) that is 100 times higher than that for RARα (Kd, 225 nM) or RARγ (Kd, 223 nM)[1].
References
[1] Germain P, et al. Rational design of RAR-selective ligands revealed by RARbeta crystal stucture. EMBO Rep. 2004;5(9):877-882. DOI:10.1038/sj.embor.7400235
