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Hesperidin dihydrochalcone can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

In a stainless steel autoclave, 100 g of hesperidin, 500 ml of 30% liquid sodium hydroxide, and 10 g of pt / c5% wet product were added. Seal well, replace three times with N2 and three times with hydrogen. The pressure is controlled at 1.5Mpa, the temperature is controlled at about 30-90 ° C, and the reaction takes about 10 hours to generate hesperidin dihydrochalcone, which is filtered and the catalyst is continuously reused. According to liquid chromatography analysis, hesperidin dihydrochalcone The yield of ketone was 93%.The reaction solution was neutralized with 31% HCl to neutrality, and then filtered. The filter cake was added to 300 ml of water and heated to complete dissolution, and then cooled to about 10 ° C, and filtered to obtain a white powdered hesperidin dihydrochalcone. The finished product was dried and had a dry weight of 90 g.