33404-78-3

Negamycin is a compound with antibacterial activity that inhibits protein synthesis by binding to the head domain of the bacterial ribosomal small subunit, leading to cell death, and also promotes misreading of near-cognate codons.

[1] Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome DOI:10.1073/pnas.1414401111