330796-57-1

5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 . It inhibits microsomal prostaglandin E₂ synthase (mPGES) when used at a concentration of 10 μM.¹

5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 (HY-121825). 5-trans U-44069 inhibits prostaglandin E2 synthase activity[1].

1. Quraishi, O., Mancini, J.A., and Riendeau, D. Inhibition of inducible prostaglandin E₂ synthase by 15-deoxy-Δ^12,14-prostaglandin J₂ and polyunsaturated fatty acids Biochem. Pharmacol. 63(6),1183-1189(2002).