320-47-8

white to light yellow crystal powder

4-Nitro-2-(trifluoromethyl)benzonitrile is a benzonitrile derivative containing trifluoromethyl and nitro substituents at the 2 and 4 positions. It can be used as an electrochemical material for lithium ion battery research. In the field of organic synthesis, it is also used in the preparation of substituted phenoxyphenyl ketones, which can be further reacted to obtain substituted 1-[4-phenoxy-2-(haloalkyl)phenyl]-2-(1,2,4-triazol-1-yl)ethanol compounds.

Potassium cyanide was added to an anhydrous acetonitrile solution of 2-chloro-5-iodobenzene 4-nitro-2-(trifluoromethyl)aniline at room temperature, and the mixture was heated at 60°C for 25 min. with the addition of an aqueous saturated sodium thiosulfate