Uses
Thiocyclam (trade name Evisect) is a broad-spectrum nereistoxin analogue insecticide used widely for agricultural applications.
Uses
Thiocyclam is used to protect against Lepidoptera, Coleoptera,
some Diptera and Thysanoptera. It is used to control Colorado beetle in
potatoes, Lepidoptera and Coleoptera pest complexes in rape, stem borers
in irrigated rice, corn borers and Tanymecus in maize, weevils and other
Coleoptera in sugar beet, stem borers in sugar cane, Lepidoptera in fruit
trees and leaf miners in vegetables.
Definition
ChEBI: An oxalate salt resulting from the formal reaction of equimolar amounts of thiocyclam and oxalic acid. A nicotinic acetylcholine receptor agonist, it was used as a broad-spectrum insecticide. It is not approved for use within the European Union.
Metabolic pathway
Thiocyclam is a propesticide of the natural product nereistoxin which is a
potent insect neurotoxin isolated from the annelid Lumbviconeveis hetevopoda.
Thiocyclam is rapidly converted into nereistoxin in biological media,
the latter being relatively stable. See the entry for cartap for some further
information on nereistoxin.
Degradation
The DT50 value for hydrolysis of thiocyclam hydrogen oxalate at pH 5
is 6 months and at pH values in the range 7-9 is 5-7 days (25 °C). It is
degraded in natural water (not specified) via nereistoxin (2) and its oxide
(3) to compounds of lower molecular weight. The rate of degradation is
increased by irradiation with light. It is degraded by sunlight, the DT50
value being 2-3 days in surface waters (PM).
