Thiocyclam is a pro-insecticide of the natural
toxin nereistoxin and is rapidly converted into the
latter in biological media. It has limited systemic activity
with stomach and contact action. It causes paralysis
by ganglionic blocking action on the insect central nervous
system. It is used as the hydrogen oxalate salt. This is converted
to the active nereistoxin, and its oxide in soils and
plants and these are ultimately broken down into smaller
molecules.
ChEBI: An organosulfur heterocyclic compound that is 1,2,3-trithiane in which one of the hydrogens at position 5 has been replaced by a dimethylamino group. A nicotinic acetylcholine receptor agonist, it was used (particularly as its hydrogen oxalate salt, known
s thyocyclam oxalate) as a broad-spectrum insecticide, but it is also toxic to bees, fish and other aquatic organisms. It is not approved for use within the European Union.
