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CAS DataBase List
3032196-65-6
3032196-65-6
Name
TEAD-IN-10
CAS
3032196-65-6
Molecular Formula
C15H14F3NO
Molecular Weight
281.27
MOL File
3032196-65-6.mol
Synonyms
TEAD-IN-10
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Chemical Properties
Boiling point
387.0±42.0 °C(predicted)
density
1.299±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka
-1.68±0.40(predicted)
Hazard Information
Uses
TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1].
IC 50
TAED1: 14 nM (IC
50
); TAED2: 179 nM (IC
50
); TAED3: 4 nM (IC
50
)
References
[1] Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15
Supplier
TargetMol Chemicals Inc.
Telephone
15002134094
Website
https://www.targetmol.cn/
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