STING agonist-31 (Compound 40) (10 mg/kg, i.v.) inhibits tumor growth in 4T1 and CT26 tumor mice model[1].
STING agonist-31 (1 mg/kg, i.v., rats) shows T1/2: 0.697 h, AUClast: 678 h?ng/mL[1].
| Animal Model: | Mice models bearing orthotopic transplanted breast tumor (4T1) or subcutaneous transplanted colon tumor (CT26)[1] |
| Dosage: | 10 mg/kg |
| Administration: | i.v., at days 1, 4, and 7 |
| Result: | Inhibited tumor Growth. |