ChemicalBook CAS DataBase List 265646-85-3

265646-85-3

Name	Endovion
CAS	265646-85-3
Molecular Formula	C16H9BrF6N6O
MDL Number	MFCD28147607
Molecular Weight	495.18
MOL File	265646-85-3.mol

Chemical Properties

density	1.791±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble to 100 mM in DMSO and to 50 mM in ethanol
form	Solid
pka	3.95±0.10(Predicted)
color	White to off-white
Water Solubility	Water : < 0.1 mg/mL (insoluble)

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Information

Spectrum Detail

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Cell Line:	Wild -type, resistant, and transiently transfected A2780 cells.
Concentration:	10-100 μM. < /td>
Incubation Time:	18 or 4.5 h.
Reduced the maximal taurine rate constant more than 90% compared with the untreated control cells. Resulted i n an increased LRRC8A protein expression. Significantly reduced p53 and ^p21Waf1/Cip1 protein level in A2780WT cells.

Cell Line:	Capan-1, AsPC-1, BxPC-3 and H6c7 cell lines.
Concentration:	10 μM.
Incubation Time:	24 h.
Result:	Resulted in the most pronounced inhibition in all cell lines with 77 ± 26 % in Capan-1, 67 ± 9 % in AsPC-1, and 54 ± 8 % in BxPC-3 cells at +67 mV.

265646-85-3

Chemical Properties

Safety Data

Hazard Information

Biological Activity

in vitro

target

storage

Spectrum Detail

Supplier