ChemicalBook CAS DataBase List 2649154-57-2

2649154-57-2

Chemical Properties

Boiling point	857.537±65.00 °C(Press: 760.00 Torr)(predicted)
density	1.428±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility	Acetonitrile: Slightly soluble: 0.1-1 mg/ml DMSO: Sparingly soluble: 1-10 mg/ml
form	Solid
pka	12.718±0.46(predicted)
color	Light yellow to yellow

Nanjing Chemlin Chemical Co., Ltd

Telephone025-83697070 13770331960

Websitehttp://www.echemlin.cn

Shanghai YuanYe Biotechnology Co., Ltd.

Telephone 15026964105

Websitehttps://www.shyuanye.com

Shanghai Chaolan Chemical Technology Center

TelephoneQQ：65489617 13301690235

Websitehttp://www.atkchemical.com/

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840

Websitehttp://www.jm-bio.com/

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shanghai Amole Biotechnology Co., Ltd.

Telephone13370042665 18916960931

Websitehttps://www.amole.com.cn/

Guangzhou Ruidi Biotechnology Co., Ltd.

Telephone020-82099279 18988941402

Websitehttp://www.ubiochem.com/

ATK CHEMICAL COMPANY LIMITED

Telephone+undefined-21-51877795

Websitehttp://www.atkchemical.com

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Animal Model:	RA375 (10 mg/kg, ip) inhibits proteasome function and reduces ovarian tumor burden in mice^[1].
Dosage:	10 mg/kg.
Administration:	IP for a 5 days on, 2 days off cycle for two weeks.
Result:	Reduced ovarian tumor burden in mice.

Animal Model:	Female Balb/c mice^[1].
Dosage:	5, 10, 20, 40, 60, 100 mg/kg (Pharmacological Analysis).
Administration:	IP single dose.
Result:	The dose of 40 mg/kg on alternate days for two weeks produced no observable toxicities or weight loss.