259728-61-5

Funalenone is a phenalene compound isolated from Penicillium sp. FKI-1463. Funalenone inhibits HIV-1 integrase and type I collagenase.

ChEBI: Funalenone is an organic tricyclic compound that is 1H-phenalen-1-one which is substituted by hydroxy groups at positions 3,4,7, and 9, by a methoxy group at position 2, and by a methyl group at position 6. It is a collagenase inhibitor produced by Aspergillus niger. It has a role as an EC 3.4.24.3 (microbial collagenase) inhibitor and an Aspergillus metabolite. It is an organic tricyclic compound, an enone and a member of phenols. It derives from a hydride of a phenalene.

collagenases 1; HIV Integrase: 10 μM (IC₅₀)

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