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2569296-51-9
2569296-51-9
Name
MIPS-21335
CAS
2569296-51-9
Synonyms
MIPS-21335
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Chemical Properties
form
Solid
color
Off-white to light yellow
Hazard Information
Uses
MIPS-21335 is an PI3KC2α inhibitor (IC50: 7 nM). MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ (IC50: 0.043, 0.140, 0.386, 0.742 μM). MIPS-21335 has antithrombotic effect[1].
References
[1] Selvadurai MV, et al. Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation. Sci Transl Med. 2020 Jul 22;12(553):eaar8430. DOI:
10.1126/scitranslmed.aar8430
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TargetMol Chemicals Inc.
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15002134094
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https://www.targetmol.cn/
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