2556-36-7

1,4-Bis(isocyanato)cyclohexane is a reagent used in the synthesis of flame retardants based upon polyurethane.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.

Isocyanates and thioisocyanates, such as cyclohex-1,4-ylene diisocyanate(2556-36-7), are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].