ChemicalBook CAS DataBase List 252003-71-7

252003-71-7

Name	CP-547632 (hydrochloride)
CAS	252003-71-7
Molecular Formula	C20H25BrClF2N5O3S
MDL Number	MFCD20268381
Molecular Weight	568.86
MOL File	252003-71-7.mol

Chemical Properties

storage temp.	Store at -20°C
solubility	DMSO: 38.33 mg/mL (67.38 mM); Water: < 0.1 mg/mL (insoluble)
form	Solid
color	White to light yellow

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P305+P351+P338

Hazard Information

Supplier

Shanghai Lollane Biological Technology Co.,Ltd.

Telephone021-52996696，15000506266 15000506266

Websitehttp://www.bioll.com

Shanghai EFE Biological Technology Co., Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

Shanghai Chaolan Chemical Technology Center

Telephone021-QQ：65489617 15618227136

Websitehttp://www.atkchemical.com/

TOSUN PHARM

Telephone020-61855200 13326451905

Websitehttp://www.toref.cn/

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Telephone 18818260767

Websitehttp://www.chemegen.com

Shanghai hongqu biomedical technology co. LTD

Telephone 88888888888

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList873228/0.htm

Energy Chemical

Telephone021-58432009 400-005-6266

Websitehttp://www.energy-chemical.com

cjbscvictory

Telephone13348960310 13348960310

Websitehttps://www.weikeqi-biotech.com/

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840 15801484223;

Websitehttp://www.jm-bio.com/

InvivoChem

Telephone 13549236410

Websitehttps://www.invivochem.cn/

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Shanghai Tachizaki Biomedical Research Center

Telephone 18014399201

Websitehttp://www.chemlab-tachizaki.com/

Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

Shanghai Jianchao Biotechnology Co., LTD

Telephone13621743886 13621743886

Websitehttp://ats-mall.com/

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Telephone021-59167510 18117107507

Websitehttps://www.med-life.cn/

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Telephone +86-18521732826

Websitehttp://www.aladdin-e.com/

Changsha Fuzhen Biotechnology Co.，LTD

Telephone18670069958 18670069958

Websitehttps://www.chemicalbook.com/supplier/25777903/

RD International Technology Co., Limited

Telephone 18024082417

Websitehttps://www.ruidiresearch.com

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Cell Line:	Serum-deprived cells
Concentration:	1, 4, 16, 63, 250, 1000 nM
Incubation Time:	1 hours
Result:	Inhibited VEGF-stimulated VEGFR-2 phosphorylation in a dose-dependent fashion.

Animal Model:	Mice bearing tumors (75-150 mm in size)
Dosage:	6.25, 12.5, 25, 50, 100 mg/kg
Administration:	Po; daily; 10-24 days
Result:	Caused a dose-dependent inhibition of growth in Colo-205, DLD-1, and MDA-MB-231 xenografts.

Animal Model:
Dosage:	50 mg /kg
Administration:	Oral
Result:	A single oral dose of 50 mg/kg yielded plasma concentrations above 500 ng/ml for 12 hours.

252003-71-7

Chemical Properties

Safety Data

Hazard Information

Biological Activity

in vitro

in vivo

target

Supplier