ChemicalBook CAS DataBase List 22662-39-1

22662-39-1

Name	Rafoxanide
CAS	22662-39-1
EINECS(EC#)	245-148-9
Molecular Formula	C19H11Cl2I2NO3
MDL Number	MFCD00682899
Molecular Weight	626.01
MOL File	22662-39-1.mol

Synonyms

3'-CHLORO-4'-(4-CHLOROPHENOXY)-3,5-DIIODOSALICYLANILIDE DIANMILIU'AN RAFOXANIDE RAFOXANIDE 3’-chloro-4’-(p-chlorophenoxy)-3,5-diiodo-salicylanilid 3’-chloro-4’-(p-chlorophenoxy)-3,5-diiodosalicylanilide bovanide duofas flukanide mk-990 n-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo-benzamid rafoxanidum Ranide Rafoxanide BP V85 Rafoxanide, Vetranal N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide 3''-CHLORO-4''-(4-CHLOROPHENOXY)-3,5-DIIODOSALICYLANILIDE(RAFOXANIDE) RADIXGLYCYRRHIZAE.P.E 3'-Chloro-4'-(p-chlorophenoxy)-2-hydroxy-3,5-diiodobenzanilide

Chemical Properties

Melting point	168-170°
Boiling point	526.6±50.0 °C(Predicted)
density	2.050±0.06 g/cm3(Predicted)
storage temp.	0-6°C
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form	neat
pka	6.04±0.48(Predicted)
color	White to Off-White
Merck	14,8097
Major Application	agriculture environmental
InChI	InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)
InChIKey	NEMNPWINWMHUMR-UHFFFAOYSA-N
SMILES	C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)(=O)C1=CC(I)=CC(I)=C1O
CAS DataBase Reference	22662-39-1(CAS DataBase Reference)

Safety Data

WGK Germany	3
RTECS	VN7870000
HS Code	2924.29.7790
Storage Class	11 - Combustible Solids

Hazard Information

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Animal Model:	AOM induced Apc^min/+ mice^[3]
Dosage:	7.5 mg/kg
Administration:	Intraperitoneal injection (i.p.), once every 2 d for 88d
Result:	Exerted less number and size of AOM induced lesions in the colon. No significant body weight changes were observed. Detected adenomas (28.6%), advanced adenomas (67.8%) and adenocarcinoma (3.6%) in control group as adenomas (33.3%), advanced adenomas (25%%) and no obvious lesions(41.6%) were detected in treated group. Caused increased signal for p-eIF2α, CHOP and cleaved caspase-3 in tumor tissues while these signal in non-tumor colon epithelium were barely detectable.

22662-39-1

Chemical Properties

Safety Data

Hazard Information

Chemical Properties

Uses

in vivo

IC 50

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

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