CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).1 Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm, respectively. CAY10731 is selective for H2S over glutathione (GSH), cysteine, H2O3-, SO3-, and H2O2 as well as tBuO and OH radicals. It has been used to detect H2S in rat hippocampal slices and nematodes.
Uses
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes[1].
storage
Store at -20°C
References
1. Reja, S.I., Sharma, N., Gupta, M., et al. A highly selective fluorescent probe for detection of hydrogen sulfide in living systems: In vitro and in vivo applications Chemistry 23(41),9872-9878(2017).
