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Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (Ex/Em=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe2+, Fe3+, Mg2+, Ca2+, and Zn2+)[1].

[1] Shieh M, et al. Shining a light on SSP4: A comprehensive analysis and biological applications for the detection of sulfane sulfurs[J]. Redox Biology, 2022, 56: 102433. DOI:10.1016/j.redox.2022.102433